453 - Synthesis of derivatives of Chiricanine A

Professor Joseph J. Mullins PhD, Phung Tran, Divina Oweis Department of Chemistry & Physics, Le Moyne College, Syracuse, NY, United States

This poster will detail progress toward the
synthesis of derivatives of the phenolic stilbenoid Chiricanine A ((E)-2-(3-methylbut-2-enyl)-5-styrylbenzene-1,3-diol).
Chiricanine A is toxic against a. aegyptii larvae and has antifungal
properties [J. Nat. Prod. 2001, 64, 710-715]. We have
prepared novel analogs of this compound which incorporate alternate aromatic substituents
(4-fluorophenyl, 4-nitrophenyl, 2-naphthyl, 4-pyridyl, furfuryl) in place of
the unsubstituted phenyl ring.

Tuesday, March 29, 2011 08:00 PM
Material, Devices and Switches; Molecular Recognition and Self-Assembly; Heterocycles and Aromatics; Physical Organic Chemistry: Calculations, Mechanisms, Photochemistry, and High-Energy Species (08:00 PM - 10:00 PM)
Location: Anaheim Convention Center
Room: Hall B